…: journals.permissions@oup.com 2017 Smart personalized therapy is the future of medical care. 1 Cellular therapy for rejuvenation is one such therapies in aesthetic surgery that is gaining momentum. The mainstay of such therapies are fat cell injection and platelet rich plasma (PRP). However, despite…
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Smart personalized therapy is the future of medical care.1 Cellular therapy for rejuvenation is one such therapies in aesthetic surgery that is gaining momentum. The mainstay of such therapies are fat cell injection and platelet rich plasma (PRP). However, despite their increasing popularity, their mechanism of action is still unclear. This is more so when used in combination therapy, where enhanced effect has been reported.2 This article elegantly explores the role of PRP when co-cultured with adipose-derived stem cells (ASC).3 It shows that activated PRP and fresh non-activated PRP are just as good in enhancing ASC population. Implying that, surprisingly, cryopreserved PRP had little beneficial effect on ASCs. This may be due to degradation of growth factors in cryopreserved PRP, although this was not further explored.
Afshin Mosahebi, MBBS, FRCS, MBA, PhD, FRCS (Plast)
in Aesthetic Surgery Journal
Aesthetic Surgery Journal, Volume 37, Issue 6, 1 June 2017, Pages 730, https://doi.org/10.1093/asj/sjw269
Published: 22 February 2017
The described effect of PRP with or…
Journal Article